NewslettersPancreatic Cell NewsAutotaxin Secretion Is a Stromal Mechanism of Adaptive Resistance to TGFβ Inhibition in Pancreatic Ductal AdenocarcinomaBy Bob - October 3, 2023032Researchers found that autotaxin, a secreted enzyme that promotes inflammation and fibrosis by generating lysophosphatidic acid, mediated adaptive resistance to TGFβ receptor inhibition.[Cancer Research]Full Article