Dexmedetomidine Alleviates Cognitive Impairment by Promoting Hippocampal Neurogenesis via BDNF/TrkB/CREB Signaling Pathway in Hypoxic–Ischemic Neonatal Rats

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Hypoxic–ischemic brain damage (HIBD) was induced in postnatal day seven rats using the Rice-Vannucci method, and dexmedetomidine (25 μg/kg) was administered intraperitoneally immediately after the HIBD induction.
[CNS Neuroscience & Therapeutics]
Abstract