Multiple Infusions of Ex Vivo-Expanded Regulatory T Cells Promote CD163+ Myeloid Cells and Kidney Allograft Survival in Non-lymphodepleted Non-human Primates

Scientists examined the influence of autologous ex vivo-expanded polyclonal Tregs on kidney graft survival in a clinically-relevant non-human primate model. Peripheral blood Tregs were isolated and expanded using artificial antigen presenting cells.