Gut Insulin Action Protects from Hepatocarcinogenesis in Diabetic Mice Comorbid with Nonalcoholic Steatohepatitis

Using a STelic Animal Model, investigators treated male mice, which developed diabetes, nonalcoholic steatohepatitis, and HCC associated with dysbiosis upon low-dose streptozotocin and high-fat diet, with insulin or phlorizin.