NewslettersMammary Cell NewsPyrroline-5-Carboxylate Reductase 1 Reprograms Proline Metabolism to Drive Breast Cancer Stemness under Psychological StressBy Bob - October 19, 20230104Researchers identified that proline synthetase PYCR1 was critical for breast cancer stemness and tumor growth. PYCR1-synthesized proline activated cGMP-PKG signaling to enhance cancer stem-like traits.[Cell Death & Disease]Full Article