Chronic Administration of XBD173 Ameliorates Cognitive Deficits and Neuropathology via 18 kDa Translocator Protein (TSPO) in a Mouse Model of Alzheimer’s Disease

To study whether the TSPO ligand XBD173 may exert early neuroprotective effects in Alzheimer’s disease (AD) pathology, the authors investigated the impact of XBD173 on amyloid toxicity and neuroplasticity in mouse models of AD.