Lactobacillus plantarum Ameliorates NASH-Related Inflammation by Upregulating L-Arginine Production

The authors used a choline-deficient high-fat diet-induced murine model that recapitulated the critical features of human metabolic syndrome and investigated the effect of L. plantarum on nonalcoholic steatohepatitis (NASH) pathogenesis using transcriptomic, metagenomic, and immunohistochemistry analyses.