Targeting the ZNF-148/miR-335/SOD2 Signaling Cascade Triggers Oxidative Stress-Mediated Pyroptosis and Suppresses Breast Cancer Progression

Knockdown of zinc finger protein 148 (ZNF-148) suppressed malignant phenotypes, including cell proliferation, epithelial-mesenchymal transition, and tumorigenesis in vitro and in vivo, while ZNF-148 overexpression had the opposite effects.