Ergothioneine Suppresses Hepatic Stellate Cell Activation via Promoting Foxa3-Dependent Potentiation of the Hint1/Smad7 Cascade and Improves CCl4-Induced Liver Fibrosis in Mice

By
Jamie Kang
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Scientists reported that in LX-2 HSCs, ergothioneine upregulated the expression of Hint1 and Smad7 and suppressed their activation provoked by TGFβ1.
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AbstractGraphical Abstract