Mendelian Randomization Analyses Suggest a Causal Role for Circulating GIP and IL-1RA Levels in Homeostatic Model Assessment-Derived Measures of β-Cell Function and Insulin Sensitivity in Africans without Type 2 Diabetes

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Researchers evaluated associations between 11 circulating cytokines and hormones with T2D among a population of sub-Saharan Africans and tested for causal relationships using Mendelian randomization analyses.
[Genome Medicine]
Abstract