DMT1-Dependent Endosome-Mitochondria Interactions Regulate Mitochondrial Iron Translocation and Metastatic Outgrowth

Investigators showed that Divalent Metal Transporter 1 (DMT1) sustained mitochondrial iron translocation via early endosome-mitochondria interactions in triple-negative MDA-MB-231, but not in luminal A T47D breast cancer cells.