FC Receptor-Like 5 (FCRL5)-Directed CAR-T Cells Exhibit Antitumor Activity against Multiple Myeloma

Researchers designed FCRL5-directed CAR-T cells and assessed their cytotoxicity in vitro using a co-culture system and in vivo using multiple myeloma (MM) cell-derived xenograft models, specifically focusing on MM with gain of chromosome 1q21.