A Highly Efficient Cell Culture Method Using Oxygen-Permeable PDMS-Based Honeycomb Microwells Produces Functional Liver Organoids from Human Induced Pluripotent Stem Cell-Derived Carboxypeptidase M Liver Progenitor Cells

Investigators developed a highly efficient method for generating functional liver organoids from hiPSC-derived carboxypeptidase M liver progenitor cells, using a microwell structure, and enhanced maturation through direct oxygenation in oxygen-permeable culture plates.