Exploration of MELK as a Downstream of Del-1 and Druggable Targets in Triple-Negative Breast Cancer

To investigate Del-1 downregulation effect on breast cancer, scientists performed transcriptome analysis using RNA sequencing of Del-1 knockdowned MDA-MB-231 cell line Plus, to investigate the expression of Del-1 and Maternal embryonic leucine zipper kinase, mRNA levels in eight different TNBC cell lines were analyzed.