Hepatic Snai1 and Snai2 Promote Liver Regeneration and Suppress Liver Fibrosis in Mice

Investigators identified hepatic Snai1 and Snai2 as important transcriptional regulators for liver regeneration and fibrosis. Partial hepatectomy or CCl4 treatment increases occupancies of Snai1 and Snai2 on cyclin A2 and D1 promoters in the liver.