iPSC-Derived Hindbrain Organoids to Evaluate Escitalopram Oxalate Treatment Responses Targeting Neuropsychiatric Symptoms in Alzheimer’s Disease

Researchers generated hindbrain organoids containing serotonergic neurons using hiPSCs. They laid the groundwork for the application of hindbrain organoids to evaluate individual differences in disease progression, neuropsychiatric symproms development, and pharmacological treatment response.