Reprograming Immunosuppressive Microenvironment by eIF4G1 Targeting to Eradicate Pancreatic Ductal Adenocarcinoma

Investigators reported that eukaryotic initiation factor (eIF) 4G1, one of the subunits of eIF4F, was overexpressed in cancer cells and cancer-associated fibroblasts, and this correlated with poor prognosis in patients with PDAC.