Differentiating Visceral Sensory Ganglion Organoids from Induced Pluripotent Stem Cells

The authors established a protocol to differentiate human induced pluripotent stem-cell-derived visceral sensory ganglion organoids (VSGOs). They integrated VSGOs with human colon organoids on a microfluidic device and applied this axis-on-a-chip model to Alzheimer’s disease.