Delineating Transcriptomic Signatures of In Vitro Human Skeletal Muscle Models in Comparison to In Vivo References

Scientists delineated the state-of-the-art of muscle models by performing a large-scale analysis of transcriptome datasets, covering over 400 samples across 39 studies, including bulk and single-cell RNA sequencing of 2D and 3D models and their in vivo counterparts.