RDIVpSGP Motif of ASPP2 Binds to 14-3-3 and Enhances ASPP2/k18/14-3-3 Ternary Complex Formulation to Promote BRAF/MEK/ERK Signal Inhibited Cell Proliferation in Hepatocellular Carcinoma

By
Britya Ghosh
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0
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Investigators suggested that ASPP2 promoted BRAF/MEK/ERK signal activation by promoting the formation of an ASPP2/k18/14-3-3 ternary complex via the RDIVpSGP motif at the N terminus.
[Cancer Gene Therapy]
Abstract