Versican Promotes T Helper 17 Cytotoxic Inflammation and Impedes Oligodendrocyte Precursor Cell Remyelination

The authors correlated high versican-V1 expression in multiple sclerosis (MS) lesions with deficient premyelinating oligodendrocytes, and highlighted its selective upregulation amongst chondroitin sulfate proteoglycans members in experimental autoimmune encephalomyelitis lesions modeling MS.