The Gut Efflux Pump MRP-1 Exports Oxidized Glutathione as a Danger Signal That Stimulates Behavioral Immunity and Aversive Learning

Scientists showed that multidrug resistance-associated protein-1 (MRP-1) functioned in the basolateral membrane of intestinal cells to transport byproducts of cellular redox reactions to control both molecular and behavioral immunity in Caenorhabditis elegans.