Olfactory Sensory Experience Regulates Gliomagenesis via Neuronal IGF1

Researchers showed that olfaction could directly regulate gliomagenesis. In an autochthonous mouse model that recapitulated adult gliomagenesis4,5,6 originating in oligodendrocyte precursor cells, gliomas preferentially emerged in the olfactory bulb—the first relay of brain olfactory circuitry.