Wild Type and Gain of Function Mutant TP53 Can Regulate the Sensitivity of Pancreatic Cancer Cells to Chemotherapeutic Drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 Pathway Inhibitors, Nutraceuticals and Alter Metabolic Properties

By
Ishira
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To further elucidate the roles of TP53 in drug-resistance of pancreatic cancer cells, the authors introduced wild-type P53 or a control vector into two different PDAC cell lines.
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