Scientists analyzed and demonstrated that two enantiomers of naftopidil, an α1D/1A-adrenoceptor blocker, induced expression and activity of UDP-glucuronosyltransferase 2B (UGT2B) in benign prostate hyperplasia rat prostate models as well as UGT2B15 in human prostate cells, BPH-1.
[Journal of Steroid Biochemistry and Molecular Biology]