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BKM120 Sensitizes BRCA-Proficient Triple Negative Breast Cancer Cells to Olaparib through Regulating FOXM1 and Exo1 Expression

[Scientific Reports] Scientists found that dual phosphoinositide 3-kinase (PI3K) and poly (ADP-ribose) polymerase inhibition with BKM120 and olaparib significantly reduced the proliferation of BRCA-proficient TNBC cell lines.

Chronic Exposure to Microcystin-LR Increases the Risk of Prostate Cancer and Induces Malignant Transformation of Human Prostate Epithelial Cells

[Chemosphere] In vitro, over 25 weeks of microcystins-LR exposure, normal human prostate epithelial (RWPE-1) cells increased secretion of matrix metalloproteinase-2, matrix metalloproteinase-9, and colony formation, features typical for cancer cells.

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