Parkinson's disease

[Nature] Investigators report an efficient one-step conversion of isolated mouse and human astrocytes to functional neurons by depleting the RNA-binding protein PTB.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers established a humanized transplantation model of Parkinson’s disease that better recapitulates the main disease features, obtained by coinjection of preformed human α-synuclein (α-syn) fibrils and adeno-associated virus expressing human wild-type α-syn unilaterally into the rat substantia nigra.

[Sunovion Pharmaceuticals, Inc.] Sunovion Pharmaceuticals, Inc. announced that Health Canada has approved apomorphine HCI soluble film for the acute, intermittent treatment of OFF episodes in patients with Parkinson’s disease.