UC-MSCs

[Heliyon] Scientists tested the effects of Piper betle L. from Vietnam on fibroblasts and umbilical cord (UC)-derived mesenchymal stem cells from human UC on the scratch assay.

[Cell Death & Disease] Downregulating chitinase-3-like protein 1 mitigated the ability of human umbilical cord-mesenchymal stem cells to inhibit T cell activation, proliferation and inflammatory cytokine secretion in vitro.

[Journal of Nanobiotechnology] Exosomes isolated from umbilical cord mesenchymal stem cells MSCs (ucMSC-Exo), MIF engineered ucMSCs (MIF-Exo) and MIF downregulated ucMSCs were used to investigate cellular protective function in human umbilical vein endothelial cells and H9C2 cardiomyocytes under hypoxia and serum deprivation and infarcted hearts in rats.

[Stem Cell Research & Therapy] Investigators performed expression profiling of exosome-miRNAs from human umbilical cord mesenchymal stem cells (MSCs) and murine compact bone MSCs to investigate their immunoregulation effects in acute graft-versus-host disease.

[Rejuvenation Research] Researchers isolated exosomes derived from umbilical cord MSCs grown in a 3D culture system and explored their ability to modulate the photo-aging of HaCaT keratinocytes.

[Stem Cell Research & Therapy] Burn-derived MSCs- and umbilical cord-MSCs were compared using immunophenotyping, multi-lineage differentiation, seahorse analysis for glycolytic and mitochondrial function, immune surface markers, and cell secretion profile assays.