acute myeloid leukemia

[Leukemia] Researchers investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.

[Leukemia] Scientists investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.

[Cancer Discovery] Scientists generated ex vivo drug response and multi-omics profiling data for a prospective series of 252 samples from 186 acute myeloid leukemia patients. Functional precision medicine tumor board integrated clinical, molecular and functional data for application in clinical treatment decisions.

[Molecular Cancer Research] Researchers revealed the breadth of SWI/SNF dependency in leukemia and supported targeting SWI/SNF catalytic function as a potential therapeutic strategy in acute myeloid leukemia.

[Apollomics, Inc.] Apollomics, Inc. announced that the first patient has been successfully dosed in a Phase III clinical trial of APL-106 for the treatment of adults with relapsed or refractory acute myeloid leukemia in China.

[Modern Pathology] Classification of myeloid neoplasms with isolated isochromosome i(17q) is controversial. Most cases fall within the WHO unclassifiable myelodysplastic/myeloproliferative neoplasms (MDS/MPN-U) category. Researchers undertook a multi-institutional retrospective study of 92 adult MDS/MPN-U cases from eight institutions.