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astrocytes

Revisiting Astrocyte to Neuron Conversion with Lineage Tracing In Vivo

[Cell] Using stringent lineage tracing in the mouse brain, investigators showed that the presumed astrocyte-converted neurons were actually endogenous neurons.

Glial and Myeloid Heterogeneity in the Brain Tumor Microenvironment

[Nature Reviews Cancer] The authors discuss the immune modulatory functions of microglia, monocyte-derived macrophages and astrocytes in brain metastases and glioma.

Cend1 and Neurog2 Efficiently Reprogram Human Cortical Astrocytes to Neural Precursor Cells and Induced-Neurons

[International Journal of Developmental Biology] Scientists investigated the neuronal reprogramming capacity of CEND1 and/or Neurogenin-2 (NEUROG2) upon their overexpression on primary human adult cortical astrocytes.

Investigating Receptor-Mediated Antibody Transcytosis Using Blood–Brain Barrier Organoid Arrays

[Fluids and Barriers of the CNS] Investigators applied a novel bioengineering approach to generate human blood-brain barrier organoids by the self-assembly of astrocytes, pericytes and brain endothelial cells with unprecedented throughput and reproducibility using micro patterned hydrogels.

Low Temperature Plasma Irradiation Products of Sodium Lactate Solution That Induce Cell Death on U251SP Glioblastoma Cells Were Identified

[Scientific Reports] Scientists quantified several major chemical products, such as pyruvate, formate, and acetate, in plasma-activated L-sodium lactate solution by nuclear magnetic resonance analysis.

circFLNA Promotes Glioblastoma Proliferation and Invasion by Negatively Regulating miR-199-3p Expression

[Molecular Medicine Reports] Researchers aimed to identify differentially expressed circular RNAs in glioblastoma. Reverse transcription‑quantitative PCR was used to analyze the expression levels of circFLNA.

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