breast cancer

[Oncogene] Scientists revealed that ERK5 was critical for maintaining the invasive capability of TNBC cells through FAK activation, and reported that a high level of ERK5 is a predictive marker of metastatic breast cancer.

[npj Breast Cancer] The receptor-interacting protein kinase 1 (RIPK1) was identified by researchers to have negatively mediated Aquaporin-driven TNBC progression and metastasis, identifying it as a potential therapeutic target for TNBC.

[npj Breast Cancer] Researchers examined HER2-positive cell line responses to inhibition with lapatinib to characterize transcriptional and epigenetic changes.

[Cancers] Scientists silenced Syndecan-1 in TNBC cell lines using a 3D human umbilical vein endothelial cell co-culture system to study its role in angiogenesis.

[IMV, Inc.] IMV, Inc. announced that its lead compound, maveropepimut-S will be investigated in patients with hormone receptor positive/HER2-negative breast cancer.

[The University of British Columbia] Dr. Connie Eaves was recognized for her development of robust functional methods to quantify and characterize distinct types of primitive blood and mammary cell precursors- now considered gold standards.