breast cancer

[BMC Cancer] Researchers investigated the effect of 10 serotoninergic receptor ligands on viability of MCF7, SKBR3 and MDA-MB231 breast cancer cells and focused on their potential ability to affect Tamoxifen responsiveness in ER+ cells.

[Journal of the American Chemical Society] Researchers demonstrated approximately 3-fold higher doxorubicin internalization in inflammatory breast cancer cells compared to healthy breast epithelial cells, leading to targeted cell death at concentrations below the IC50 of free doxorubicin.

[Cancer Chemotherapy and Pharmacology] The authors provide insight into the mechanistic pathway(s) of doxorubicin at levels found within patients and establish the magnitude of effect for each mechanism.

[Journal of Cellular and Molecular Medicine] Scientists review the recent progress of TNBC research in transcriptomics and proteomics to identify possible therapeutic goals and improve the survival of patients with TNBC.

[Communications Biology] Researchers developed a tool, named BrewerIX, that provided comprehensive information about the allelic expression of a large, manually-curated set of imprinted and X-linked genes.

[Cell Death & Disease] Scientists investigated the expression profiles and biological effects of fascin actin-bundling protein 1 (Fascin) in breast cancer.