breast cancer

[Cell Cycle] Scientists demonstrated that chrysin impaired genomic stability in MCF-7 and BT474 cells, inhibited cell survival and enhanced the sensitivity of MCF-7 cells to chemotherapeutic drugs.

[Aging] Breast cancer cells were transfected with N-glycosylation mutation EpCAM plasmid to express deglycosylated EpCAM. Investigators showed that deglycosylated EpCAM promoted autophagy in breast cancer cells.

[Breast Cancer Research] Researchers explored whether circCCDC85A could function as a miR-550a-5p sponge and influence breast cancer progression and found novel evidence that circCCDC85A inhibited the progression of breast cancer by functioning as a molecular sponge of miR-550a-5p to enhance MOB1A expression.

[Lancet Oncology] The authors discuss the rationale and summarize the clinical evidence for the use of PET–MRI in the diagnosis, staging, prognosis, tumor phenotyping, and assessment of treatment response in breast cancer.

[Cancer and Metastasis Reviews] Oncobiosis in breast cancer supports invasion, metastasis, and recurrence by supporting cellular movement, epithelial-to-mesenchymal transition, cancer stem cell function, and diapedesis. The microbiome provides novel leverage on breast cancer that should be exploited for better management of the disease.

[Theranostics] Researchers evaluated the anticancer potential of Egyptian scorpion Leiurus quinquestriatus venom or human Wharton's jelly-derived mesenchymal stem cells conditioning medium/conditioning medium against breast cancer cell line as an alternative effective cancer biotherapy.