cell proliferation

[Neoplasia] Nuclear enriched abundant transcript 1 (NEAT1) depletion inhibited prostate cancer cell aerobic glycolysis accompanied by the reduction of lactate levels in the medium.

[Cellular & Molecular Biology Letters] The authors suggested that miR-5195-3p functioned as a tumor suppressor by targeting Cyclin L1 (CCNL1) in prostate cancer.

[Bioorganic & Medicinal Chemistry Letters] The antiproliferative activity of target compounds in four human cancer cells, PC-3 (human prostate cancer cell), MCF-7 (human breast cancer cell), HepG-2 (human hepatoma cell) and MGC-803 (human gastric cancer cell), was evaluated by thiazole blue.

[Cell Cycle] A biotin-microRNA pull-down assay was performed to identify potential miRNAs. qRT-PCR was used to verify the KRT18 and miR-186-3p levels.

[Scientific Reports] Scientists utilized the strategy of iterative gene pairing to construct a tumor-specific immune-related lincRNA pairs signature, which did not require specific expression levels, as an indicator of patient outcomes.

[American Journal of Obstetrics and Gynecology] The authors identified the effect of hyperglycaemia on placentas of gestational diabetes mellitus (GDM) women with macrosomia and normal pre-pregnancy body mass index (BMI), and uncover the molecular mechanism of hyperglycemia on trophoblast cells in vitro.