cell transplantation

[International Journal of Cancer] Investigators introduced a CD33-directed third-generation CAR T cell product for the treatment of patients with acute myeloid leukemia.

[Humanigen, Inc.] Humanigen, Inc. announced it plans to support a Phase II/III study to evaluate lenzilumab for the early treatment of acute graft versus host disease following allogeneic hematopoietic stem cell transplantation in collaboration with IMPACT.

[Scientific Reports] The genomic regions ranging from 500 base pairs upstream to 500 base pairs downstream of the eight SNPs that were reported as transplantation determinants by Petersdorf et al. were analyzed to evaluate whether genetic variants were associated with the survival status of patient

[Scientific Reports] Scientists revealed that three SNPs located in the intron or 3’-UTR of HLA-DOB regions are associated with the survival of patients in the recipient and donor-recipient matching groups, as well as cytomegalovirus infection/reactivation in the donor-recipient matching group.

[Bone Marrow Transplantation] Scientists reported on 318 patients with acute leukemia, receiving donor lymphocyte infusion in complete hematologic remission after allogeneic stem cell transplantation.

[Stem Cells International] The authors evaluated the capability of human umbilical cord mesenchymal stromal cells mixed with hyaluronan to treat osteoarthritis in a rabbit model.