circulating tumor cells

[Nature Communications] Scientists evaluated 19 protocols for single cell small RNA sequencing on MCF7 cells spiked with 1 pg of 1,006 miRNAs.

[International Journal of Molecular Sciences] The authors review the available literature on plasma circulating tumor cells, cell-free tumors, circulating cell-free microRNAs, and circulating extracellular vesicles for the diagnosis and monitoring of brain tumor.

[Breast Cancer Research and Treatment] Scientists reported that the dissemination of circulating tumor cells, circulating cancer-associated fibroblasts, and clusters was an early event in breast cancer (BC) progression, and they found these clusters in all clinical stages of BC.

[International Journal of Molecular Sciences] The authors assessed whether circulating tumor cells (CTCs) in peripheral blood could serve as a disease surrogate, focusing on CD44 and CD74 expression as prognostic markers for brain metastases.

[Nature Communications] Scientists revealed that the transcriptional dynamics of circulating tumor cells were associated with stress response, cell cycle and immune-evasion signaling during hematogeneous transportation.

[Prostate] Researchers showed that anti-androgen enzalutamide (ENZA) resistant prostate cancer cells used more mitochondrial metabolism leading to higher ox-phos as compared to the ENZA-sensitive cells and could become vulnerable to mitochondrial metabolism targeted therapies.