colorectal cancer

[Immunity] The composition of the intestinal microbiota is associated with both the development of tumors and the efficacy of anti-tumor immunity. Researchers examined the impact of microbiota-specific T cells in anti-colorectal cancer immunity.

[Molecular Oncology] Scientists found that both Sirtuin 1 (SIRT1) and SIRT1 phosphorylated on serine 27 were coordinately upregulated in colon cancer patients’ tissues and human colon cancer cell lines.

[Journal of Nanobiotechnology] Researchers outline the current challenges and forthcoming research perspective for high performance and fostering advanced MNPs in colorectal cancer treatment.

[Molecular Oncology] The authors investigated whether drug responses of organoids correlated with clinical responses of matched patients and disease progression of patients.

[Cell Biology and Toxicology] Researchers revealed that USP39 was associated with colon cancer cells sensitivity to cisplatin. Depletion of USP39 enhanced the cisplatin-induced apoptosis in HCT116 cells.

[Journal of Experimental & Clinical Cancer Research] The authors investigated whether transmembrane serine protease 4 (TMPRSS4) confered cancer stem–like properties to prostate cancer cells and characterized the underlying mechanisms.