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COVID-19

Characterization of Humoral and SARS-CoV-2 Specific T Cell Responses in People Living with HIV

[Nature Communications] The authors showed that the majority of people living with HIV with ART suppressed HIV viral load, mounted a detectable adaptive immune response to SARS-CoV-2.

Increased Lethality in Influenza and SARS-CoV-2 Coinfection Is Prevented by Influenza Immunity but Not SARS-CoV-2 Immunity

[Nature Communications] Scientists examined the disease outcome of influenza A virus and SARS-CoV-2 coinfection in K18-hACE2 mice.

Hamster Organotypic Modeling of SARS-CoV-2 Lung and Brainstem Infection

[Nature Communications] Researchers developed and characterized two new organotypic cultures from hamster brainstem and lung tissues that offered a unique opportunity to study the early steps of viral infection and screening antivirals.

A Phase I/II Dose-Escalation Multi-Center Study to Evaluate the Safety of Infusion of Natural Killer Cells or Memory T Cells as Adoptive Therapy in...

[Trials] In the Phase I trial, 18 patients with COVID-19-related pneumonia and/or lymphopenia with no oxygen requirement or with an oxygen need of less than or equal to 2.5 liters per minute in nasal cannula were assigned to two arms, based on the biology of the donor and the patient.

In Vivo Characterization of Emerging SARS-CoV-2 Variant Infectivity and Human Antibody Escape Potential

[Cell Reports] Human COVID-19+ or vaccinated antibody isotypes, titers, variant RBD binding, and neutralization potential are studied, revealing numerous significant correlations.

Role of miR-2392 in Driving SARS-CoV-2 Infection

[Cell Reports] Scientists showed that miR-2392 was key in driving downstream suppression of mitochondrial gene expression, increasing inflammation, glycolysis, and hypoxia as well as promoting many symptoms associated with COVID-19 infection.

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