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endothelial cells

IL-6-Induced FOXO1 Activity Determines the Dynamics of Metabolism in CD8 T Cells Cross-Primed by Liver Sinusoidal Endothelial Cells

[Cell Reports] Scientists reported that high-level mitochondrial respiration and constitutive low-level glycolysis supported liver sinusoidal endothelial cells scavenger and sentinel functions

Heparanase Promotes Endothelial-to-Mesenchymal Transition in Diabetic Glomerular Endothelial Cells through Mediating ERK Signaling

[Cell Death Discovery] Researchers determined the effect and potential mechanism of Heparanase on glomerular endothelial cells phenotype under high-glucose conditions.

MiR-29b-3p Inhibits the Inflammation Injury in Human Umbilical Vein Endothelial Cells by Regulating SEC23A

[Biochemical Genetics] The authors investigated the effects of miR-29b-3p on the inflammation injury of HUVECs induced by lipopolysaccharide and explored the underlying mechanisms.

Functional Noncoding SNPs in Human Endothelial Cells Fine-Map Vascular Trait Associations

[Genome Research] Together with information from genome-wide association studies or vascular disease traits, scientists tested the ability of 34,344 variants to perturb enhancer function in endothelial cells using the highly multiplexed STARR-seq assay.

Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation

[Circulation Research] Mouse models of atherosclerosis in endothelial cell-specific-Bach1 knockout mice were used to study the role of BTB and CNC homology 1 (BACH1) in the regulation of atherogenesis and the underlying mechanisms.

Endothelial Cell Ferroptosis Mediates Monocrotaline-Induced Pulmonary Hypertension in Rats by Modulating NLRP3 Inflammasome Activation

[Scientific Reports] The effects of the ferroptosis inhibitor ferrostatin-1 on endothelial cell ferroptosis and pulmonary vascular remodelling in monocrotaline-induced rats were studied in vitro and in vivo.

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