endothelial cells

[Toxicology in Vitro] Vitronectin receptor (VTNR)-expressing HUVECs were used to determine the effects of endocrine disrupting chemicals and endogenous hormones on cell adhesion to vitronectin-coated surfaces, and on VTNR activation.

[Environmental Pollution] Researchers found that in terms of metabolic activity, endothelial cells were much more sensitive to PFOS than fibroblasts or epithelial cells, and concluded that PFOS possesses antiangiogenic properties.

[Circulation] Genetic fate mapping results revealed that a subset of cardiac endothelial cells transiently expressed αSMA and Zeb1 during embryonic valve formation and transdifferentiated into mesenchymal cells through EndoMT.

[Circulation Research] VE-cadherin was an essential scaffolding protein to maintain pro-lymphangiogenic signaling nodes at the plasma membrane, which was required for the development and adult maintenance of cardiac lymphatics, but not for cardiac function basally or after injury.

[EMBO Molecular Medicine] Scientists identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal endothelial cell (EC), although LIF had been mainly characterized as an EC growth inhibitor and an anti-angiogenic molecule.

[Developmental Cell] Scientists describe how microenvironmental tissue-specific biophysical, biochemical, immune, and inflammatory cues dictate the specialization of endothelial cells with zonated functions.