endothelial cells

[European Respiratory Journal] Pirfenidone treatment attenuated pulmonary remodelling in the bleomycin-model, but aggravated pulmonary inflammation, fibrosis, and vascular remodelling in Fra-2 TG mice.

[Scientific Reports] Researchers examined the role of interleukin-6 (IL-6) in defective angiogenesis mediated by leucine-rich α-2-glycoprotein 1 (LRG1). IL-6 treatment induced LRG1 expression in endothelial cells and ex vivo angiogenesis cultures and promoted vascular growth with reduced mural cell coverage.

[Neuro-Oncology] The authors established the relevance of interclonal cross-talk between MYC-driven and non-MYC-driven medulloblastoma cells.

[Small] LCL/ZnO could selectively regulate tumor-derived endothelial cells (TECs) and specifically kill tumor cells, by responding to different H2O2 gradients in TECs and tumor cells.

[Journal of Thrombosis and Haemostasis] Engineered microvessels were lined with human endothelial cells, cultured under flow, and activated to release Von Willebrand factor (VWF) and formed transluminal VWF fibers.

[Journal of Controlled Release] Scientists found that exosomes from primary brain tumors could upregulate the expression of lipocalin-2 in bEnd.3 brain microvascular endothelial cells