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endothelial cells

Schwann Cells Promote Prevascularization and Osteogenesis of Tissue-Engineered Bone via Bone Marrow Mesenchymal Stem Cell-Derived Endothelial Cells

[Stem Cell Research & Therapy] The authors cultured rat Schwann cells, aortic endothelial cells, and bone marrow-derived mesenchymal stem cells (BM-MSCs) and then obtained BM-MSC-derived induced endothelial cells and induced osteoblasts.

Circ_001209 Aggravates Diabetic Retinal Vascular Dysfunction through Regulating miR-15b-5p/COL12A1

[Journal of Translational Medicine] Downregulation of miR-15b-5p under HG conditions promoted proliferation, migration, and tube formation of human retinal vascular endothelial cells.

SIRT6 Inhibits Inflammatory Response through Regulation of NRF2 in Vascular Endothelial Cells

[International Immunopharmacology] Scientists showed that TNF-α significantly reduced the expression of SIRT6 protein and mRNA in a concentration- and time-dependent manner and increased the expression of monocyte chemotactic protein 1, interleukin (IL) -6 and IL-1β in human umbilical vein endothelial cells.

TAGLN, a Canonical Marker of Smooth Muscle Cells, Is Present in Endothelial Cells and Involved in Angiogenesis

[Journal of Cell Science] Human umbilical vein endothelial cells (HUVECs) elongated, activated TAGLN promoter and increased TAGLN transcripts in angiogenesis model. Genetic disruption of TAGLN augmented angiogenic behaviors of HUVECs, as did the disruption of TAGLN2 and TAGLN3 genes.

Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure

[Circulation] Investigators generated tissue-specific "loss-" and "gain-of-function" models for endothelial nitric oxide synthase by using cell-specific Cre-induced gene inactivation or reactivation.

Endothelial Cell-Derived Apelin Inhibits Tumor Growth by Altering Immune Cell Localization

[Scientific Reports] In MC38 tumors, only endothelial cells (ECs) strongly express APJ, a cognate receptor for Apelin, indicating that EC-derived Apelin might regulate tumor formation in an autocrine manner.

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