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endothelial cells

Brain Endothelial PTEN/AKT/NEDD4-2/MFSD2A Axis Regulates Blood-Brain Barrier Permeability

[Cell Reports] Scientists showed that cerebrovascular endothelial cell-specific deletion of Pten resulted in a dramatic increase in vesicular transcytosis by the reduction of major facilitator superfamily domain-containing 2a, leading to increased transcellular permeability of the blood-brain barrier.

Coordination of Endothelial Cell Positioning and Fate Specification by the Epicardium

[Nature Communications] Researchers used single-cell RNA sequencing at key developmental timepoints to interrogate cellular contributions to coronary vessel patterning and maturation.

Endothelial Progenitor Cells Modulate the Phenotype of Smooth Muscle Cells and Increase Their Neointimal Accumulation following Vascular Injury

[Thrombosis and Haemostasis] Researchers examined the influence of endothelial progenitor cells on features of smooth muscle cells pivotal for their impact on injury-induced neointima formation including proliferation, migration, and phenotype switch.

CD36 Promotes Vasculogenic Mimicry in Melanoma by Mediating Adhesion to the Extracellular Matrix

[BMC Cancer] Human vasculogenic mimicry (VM)-competent melanoma cell lines were examined for their VM potential using the in vitro angiogenesis assays, together with inhibition studies using small interfering RNA and blocking monoclonal antibodies.

Biological Effects of XyloCore, a Glucose Sparing PD Solution, on Mesothelial Cells: Focus on Mesothelial-Mesenchymal Transition, Inflammation and Angiogenesis

[Nutrients] Researchers evaluated at a molecular level the effects of XyloCore, a new peritoneal dialysis solution with a low glucose content, in mesothelial and endothelial cells.

miRNA-1246 in Extracellular Vesicles Secreted from Metastatic Tumor Induces Drug Resistance in Tumor Endothelial Cells

[Scientific Reports] The authors found that treatment of highly metastatic tumor-conditioned medium induced resistance to 5-fluorouracil with interleukin-6 upregulation in endothelial cells.

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