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glomerular endothelial cells

Heparanase Promotes Endothelial-to-Mesenchymal Transition in Diabetic Glomerular Endothelial Cells through Mediating ERK Signaling

[Cell Death Discovery] Researchers determined the effect and potential mechanism of Heparanase on glomerular endothelial cells phenotype under high-glucose conditions.

GlomSpheres as a 3D Co-Culture Spheroid Model of the Kidney Glomerulus for Rapid Drug-Screening

[Communications Biology] Co-cultured using a magnetic spheroid formation approach, conditionally immortalised human podocytes and glomerular endothelial cells deposited mature, organized isoforms of collagen IV and Laminin.

CRISPR/Cas9-Engineered HLA-Deleted Glomerular Endothelial Cells as a Tool to Predict Pathogenic Non-HLA Antibodies in Kidney Transplant Recipients

[Journal of the American Society of Nephrology] The authors designed a non-human leukocyte antigen (HLA) antibody detection immunoassay using HLA class I and II–deficient glomerular endothelial cells that had been previously generated through CRISPR/Cas9-induced B2M and CIITA gene disruption.

Renal Microvascular Endothelial Cell Responses in Sepsis-Induced Acute Kidney Injury

[Nature Reviews Nephrology] Comprehensive studies are needed to investigate the relationships between segment-specific changes in the microvasculature and kidney function loss in sepsis-AKI.

Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus

[Journal of the American Heart Association] Primary podocytes were isolated and subjected to analysis of Wnt signaling and fatty acid metabolism. Conditioned media from primary podocytes was transferred to glomerular endothelial cells.

TRIM27 Contributes to Glomerular Endothelial Cell Injury in Lupus Nephritis by Mediating the FoxO1 Signaling Pathway

[Laboratory Investigation] Researchers detected the expression of the tripartite motif-containing 27 (TRIM27) protein in glomerular endothelial cells in vivo and in vitro.

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