hematopoietic stem cells

[Haematologica] Investigators evaluated the response to inotuzumab ozogamicin in 31 relapsed/refractory B cell acute lymphoblastic leukemia patients with extramedullary disease.

[Cell Reports] The authors identified renal Klotho and inorganic phosphate as extrinsic factors that antagonistically regulate HSC maintenance in the bone marrow.

[Journal of Cardiology] The authors review the key of JAK2V617F-mediated clonal hematopoiesis including identification, prevalence, and biological impacts, linking to cardiovascular diseases and the related mechanisms.

[Environmental Science and Pollution Research] The authors investigated the effect of these two aforementioned substances on the clonogenic capacity of umbilical cord blood hematopoietic stem cells.

[Arteriosclerosis Thrombosis and Vascular Biology] Scientists discuss key findings from the latest research that give insight into the mechanisms by which clonal expansion of vascular cells contributes to disease pathology.

[Environmental Science and Pollution Research] Scientists investigated the effect of Bisphenol A and diethylhexyl phthalate on the clonogenic capacity of umbilical cord blood HSCs.