hepatic cells

[Life Sciences] Researchers investigated the role of survivin protein in early fibrogenic activation of hepatic stellate cells and fibrosis progression in chronic liver injury.

[Scientific Reports] Investigators found that miR-571 inhibited the apoptosis of human hepatic stellate cells and promoted cell proliferation and migration. Its up regulation promoted the expression of Notch3 and Jagged1, and promoted the expression of related fibroblasts.

[Cell Reports] Scientists showed that Myc-driven hepatocellular carcinoma was dramatically aggravated in mice with hepatocyte-specific Ptpn11/Shp2 deletion.

[Journal of Cellular Biochemistry] Researchers examined the role of Bcl2-associated athanogene (BAG3) to activate human fibroblasts in releasing cytokines capable of supporting tumor progression.

[Hepatology] Hepatitis B virus infected HepG2-NTCP were treated with tenofovir disoproxil fumarate, Toll-like receptor 7/8 agonists, TLR7/8 conditioned media collected from immune cells, or RNAi using short-interfering RNAs.

[Journal of Hepatology] Live cell imaging, histological, biochemical, and molecular studies were used to investigate the mechanisms that underlie the extracellular and intracellular action of rhMG53 in hepatoprotection.