islets

[ACS Biomaterials Science & Engineering] Hydrogel prepared with alginate and the pancreatic extracellular matrix was assessed for the beneficial outcomes on encapsulated insulin-producing cells.

[JCI Insight] Scientists reported expression of angiotensin-converting enzyme 2 in pancreatic islet, ductal, and endothelial cells in non-human primates and humans.

[Journal of Cellular Physiology] Scientists validated the effect of fetuin-A release and lipid induced apoptosis in mouse insulinoma cell line MIN6.

[Molecular Metabolism] Researchers introduced SNAPf-tag into the N-terminal segment of GPR56 to enable monitoring of GPR56 cellular activity in situ.

[Journal of Molecular Endocrinology] Scientists found that an evolutionarily conserved region located approximately 40 kbp downstream of the transcription start site of Slc2a2 functioned as an active enhancer in the MIN6 β-cell line.

[Journal of Molecular Endocrinology] Researchers investigated the mechanism of dexamethasone-induced pancreatic β-cell apoptosis through the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway in cultured cells and isolated mouse islets.