lung cancer

[Journal of Translational Medicine] Membrane progesterone receptor α was deregulated within lung adenocarcinoma (LUAD) tissue samples; increased membrane progesterone receptor α contributed to a higher microvessel density in LUAD tissues.

[Molecular Therapy Oncolytics] Scientists explored the biological function of circSHKBP1 in NSCLC. CircSHKBP1 was found to be upregulated in NSCLC tissues and cell lines and was enriched in exosomes derived from NSCLC cells.

[Cell Death & Disease] The authors found that the expression of REV1 was significantly upregulated in lung cancer tissues compared with matched adjacent tissues and was associated with poor prognosis.

[Chemico-Biological interactions] Scientists discuss the medical value of nutraceuticals briefly and their ability to mitigate various inflammatory lung diseases through targeting inhibition of NF-κB.

[Signal Transduction and Targeted Therapy] Scientists identified two 4q12 long noncoding RNAs LCETRL3 and LCETRL4 which could significantly dimmish EGFR-TKIs efficiency.

[Thoracic Cancer] GEPIA database was employed to reveal the expression level of Ovarian tumor protease domain-containing protein 1 (OTUD1) in addition to Krüppel- like factor 4 (KLF4) in NSCLC tissue samples and prove the correlation between OTUD1 and KLF4.