lung cancer

[Cell Death & Disease] Scientists demonstrated that transmembrane protein (TMEM) 116 was highly expressed in NSCLC tissues and cell lines.

[Cancer Science] Researchers demonstrated that high expression of karyopherin α2 was positively correlated with radioresistance and CSC properties in lung adenocarcinoma cells.

[Cell Death Discovery] Researchers showed that gefitinib significantly induced downregulation of Sterol Regulator Element Binding (SREBP1) in therapy-sensitive cells.

[Biochemical and Biophysical Research Communications] NSCLC cell lines with acquired radioresistance to X-rays were obtained through fractionated irradiation. The differentially expressed proteins between the self-established radioresistant NSCLC cell line A549-R11 and control were measured by proteomic analysis.

[Cell Death & Disease] The authors detected a higher concentration of CD73+ tumor-derived extracellular vesicles enriched in exosomes in central and peripheral body fluids of glioblastoma patients than in those of patients with other brain tumors.

[Cell Reports] Researchers showed that the expression of TIAM1, an activator of the small GTPase RAC1, was associated with a neuroendocrine gene program.