lymphocytes

[Biochemical Pharmacology] Investigators summarize recent progress in relevant studies regarding the physiological and pathophysiological functions of MALT1, post-translational modifications of MALT1 and its role in B cell- and T cell- related diseases.

[Journal of Reproductive Immunology] Investigators hypothesized that decidual leukocytes were altered by maternal SARS-CoV-2 infection in pregnancy and that this decidual immune response was shaped by the timing of infection during gestation.

[Science Signaling] In their investigation of how BCR signaling was restored in Cd45−/− cells, scientists found that the coreceptor CD22 switched from an inhibitory to a stimulatory function in these cells.

[Science Signaling] Researchers demonstrated that PKCθ/β-dependent CARD11 phosphorylation also suppressed CARD11 functions in T or B cells.

[Journal of Immunology] Investigators developed a protocol to generate stable numbers of liver-located CD8 T cells, and used intravital microscopy to record movement patterns of CD8 T cells in livers of live mice.

[Cell Reports] Scientists investigated the impact of mammary tumorigenesis on regulatory T cells in distant organs and how this affected multi-organ metastatic disease.